Initial Orthostatic Hypotension in the Young Is Attenuated by Static Handgrip

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Initial orthostatic hypotension is unrelated to orthostatic tolerance in healthy young subjects.

The physiological challenge of standing upright is evidenced by temporary symptoms of light-headedness, dizziness, and nausea. It is not known, however, if initial orthostatic hypotension (IOH) and related symptoms associated with standing are related to the occurrence of syncope. Since IOH reflects immediate and temporary adjustments compared with the sustained adjustments during orthostatic s...

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Several studies have shown that standing up is a frequent (3-10%) trigger of loss of consciousness both in young and old subjects. An exaggerated transient BP (blood pressure) fall upon standing is the underlying cause. IOH (initial orthostatic hypotension) is defined as a transient BP decrease within 15 s after standing, >40 mmHg SBP (systolic BP) and/or >20 mmHg DBP (diastolic BP) with sympto...

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ژورنال

عنوان ژورنال: The Journal of Pediatrics

سال: 2010

ISSN: 0022-3476

DOI: 10.1016/j.jpeds.2010.01.035